Cytomix administration reduced mean myocyte cell width (representative microphotographs in A, mean data in B). Concomitant administration of MitoTEMPOL prevented cytomix-mediated reductions in myocyte width. Data were obtained from n = 5 plates of cells/group with the following numbers of cells counted (n = 1,440 for controls, n = 720 for cytomix, n = 360 for MitoTEMPOL, and n = 360 for cytomix + MitoTEMPOL). In B, boxes represent 1 SD; center line in the box indicates the mean, and whiskers indicate the minimum and maximum values. *Statistical significance.