Table 1.

Validated skin assessments commonly used in atopic dermatitis studies

Assessment	Assessment type	Description	Outcome
TEWL	Biophysical	Tewa Meter or similar device directly measures water loss from skin in g/m2/h	High values indicate defective barrier function; low values indicate tight barrier
Corneometry	Biophysical	Corneometer indirectly measures hydration by detecting capacitance changes due to water content in skin	High values indicate greater hydration; low values indicate dry skin
SCORAD	Clinical	Measure of signsa and symptomsb on scale of 0–103	High score indicates more severe clinical phenotype
EASI	Clinical	Measure of signsc on scale of 0–72	High score indicates more severe clinical phenotype
ADSI	Clinical	Measure of signs and symptomsd on scale of 0–15	High score indicates more severe clinical phenotype

ADSI Atopic Dermatitis Severity Index, EASI Eczema Area and Severity Index, SCORAD Scoring Atopic Dermatitis, TEWL transepidermal water loss

^aRedness, swelling, oozing/crusting, excoriation, lichenification, dryness

^bItching, sleeplessness

^cErythema, edema/papulation, excoriation, lichenification

^dErythema, pruritus, exudation, excoriation, lichenification