Table II.

Parameter Value Estimates, Standard Errors (SE), and Coefficient of Variation (CV%) from Effect Compartment PK-PD Model Describing Inhibition of Rhesus Olfaction

Test Compound	EC50 (μM)			ke0 (hr−1)
	Estimate	SE	CV%	Estimate	SE	CV%
6	10.21	1.60	16	2.20	0.68	31
13	13.66	2.97	22	3.22	1.02	32
14	11.79	2.55	22	1.14	0.25	22
16	1.62	1.33	82	0.66	0.25	38
18	5.97	0.86	14	1.39	0.36	26
21	1.25	0.45	36	0.62	0.42	67
22	3.11	0.66	21	3.74	1.87	50
24	0.78	0.18	23	1.65	0.32	20
25	1.40	0.33	23	0.74	0.34	46
27	1.24	1.19	95	0.55	0.51	93