Figure 1.

Neurotransmitter transporters and receptors binding profile of viloxazine. Representative results of binding competition assays of viloxazine (10 µM). Viloxazine binding was calculated as a percent inhibition of the binding of a radiolabeled ligand specific for each target (mean ± SEM, n = 2). Targets that presented an inhibition higher than 50% were considered a significant effect for viloxazine binding.

Abbreviations: 5-HT, serotonin; CHT-1, choline transporter; DAT, dopamine transporter; GAT, GABA transporter; NET, norepinephrine transporter; SEM, standard error of the mean; SERT, serotonin transporter.