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. 2020 Sep 4;10:14640. doi: 10.1038/s41598-020-71495-9

Table 1.

Metals detected in the saliva, limit of detection (LOD) and distribution.

Metal Salivary metal tertiles (ppb)
LOD Minimum 33rd percentile Median 66th percentile Maximum
Essential
Cobalt 0.1 0.23 0.42 0.55 0.64 1.87
Copper 10 < LOD 27.42 37.28 52.79 394.79
Manganese 5 < LOD 10.74 14.46 21.76 94.37
Molybdenum 0.2 0.24 0.82 0.95 1.20 4.49
Zinc 30 97.81 265.72 303.69 382.77 10,198.95
Other heavy metals
Antimony 0.1 0.16 2.43 2.73 3.40 13.33
Arsenic 0.2 < LOD < LOD 0.14 0.25 2.65
Barium 0.5 2.17 5.58 15.71 29.24 69.86
Beryllium 0.5 < LOD < LOD < LOD < LOD 2.49
Cadmium 0.5 < LOD 0.30 0.49 0.58 7.16
Cesium 0.2 < LOD 0.44 0.50 0.66 1.98
Lead 0.1 0.82 2.64 4.12 7.25 252.07
Mercury 0.1 < LOD < LOD 0.33 1.03 446.90
Platinum 0.1 < LOD < LOD < LOD < LOD 0.29
Thallium 0.5 < LOD < LOD < LOD < LOD 1.74
Tin 0.5 < LOD 0.77 1.62 3.08 195.03
Uranium 0.1 < LOD < LOD < LOD < LOD 0.51
Some evidence of physiological function
Chromium 0.2 0.73 1.49 1.81 2.26 10.78
Nickel 2 3.306 6.63 7.83 8.71 26.07
Tungsten 0.1 < LOD 0.11 0.20 0.25 19.34
Vanadium 0.1 < LOD 0.20 0.36 0.41 1.60

Stimulated saliva samples were obtained from 13 children age 7–17 and 48 adults aged 18–45 individuals from the Center for Oral Health Research in Appalachia Study I.