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. 2020 Sep 4;10:14654. doi: 10.1038/s41598-020-71359-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Number of biomarkers above the threshold (based on whole study population) for each patient using a common average montage. On the x-axis each of the 47 improved patients is displayed with a coded number. The first 17 patients are extra-temporal patients (E before the coded name), while the remaining 30 patients are temporal patients (T before the coded name). The y-axis represents the number of biomarkers above the specific threshold (computed separately for each biomarker) for each patient. T temporal, E extra-temporal.