Table 2.
Compounds identified from rat plasma by UHPLC-Q-Orbitrap-MS/MS.
| Analytes | RT(min) | Formula | Selected ion | Experimental mass (m/z) | Theoretical mass (m/z) | Error (ppm) | Product ions (m/z) |
|---|---|---|---|---|---|---|---|
| Coclaurine | 3.20 | C17H19NO3 | [M+H]+ | 286.14404 | 286.14377 | 0.944 | 269.12, 237.09, 175.08, 107.05 |
| Magnoflorine | 4.08 | C20H24NO4 | [M]+ | 342.17029 | 342.16998 | 0.892 | 297.11, 282.09, 265.09, 237.09 |
| Spinosin | 6.14 | C28H32O15 | [M+H]+ | 609.18195 | 609.18139 | 0.908 | 489.14, 447.13, 429.12, 411.11, 393.10, 351.09, 327.09, 297.07 |
| 6‴-feruloylspinosin | 8.14 | C38H40O18 | [M+H]+ | 785.22943 | 785.22874 | 0.878 | 447.13, 429.12, 411.11, 393.10, 351.09, 327.09, 297.08, 177.05 |
| Jujuboside A | 10.77 | C58H94O26 | [M-H + HCOOH]- | 1251.60034 | 1251.60043 | −0.078 | 1205.59, 1073.55, 911.49, 749.45, 603.39 |
| Jujuboside B | 11.14 | C52H84O21 | [M-H + HCOOH]- | 1089.54810 | 1089.54761 | 0.445 | 1043.54, 911.50, 749.45, 603.39 |
| Palmatine hydrochloride (IS1) | 10.20 | C21H22NO4 | [M]+ | 352.15448 | 352.15433 | 0.413 | 336.12, 322.11, 308.13 |
| Daidzin (IS2) | 4.66 | C21H20O9 | [M+H]+ | 417.11810 | 417.11800 | 0.219 | 255.06 |
| Astragaloside IV (IS3) | 11.10 | C41H68O14 | [M-H + HCOOH]- | 829.45813 | 829.45801 | 0.142 | 783.47 |