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Schematics of surface probe types. The 12-mer target strand t1 (dark red) binds to a complementary probe strand (blue) immobilized on the RPI sensing surface by a 3D copolymer coating. Three types of DNA probes were investigated: a complementary 12-mer strand (p1, no linker scheme) and longer probes formed by an ss strand (p2, ss-linker) or a ds strand (p2 + cp2, ds-linker) terminated with the complementary sequence. To see this figure in color, go online.
