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The interplay between liver and gut
Liver secretes bile acids to the intestinal lumen through bile ducts. When gut barrier is intact, the intestine absorbs nutrients through enterocytes and transports to the liver. When gut barrier is disrupted, microbial-derived toxins and products translocate to liver from intestine through portal vein and influence liver functions. Nutrients and microbial products can reach the systemic circulation via lymph vessels and the thoracic duct.
