Figure 6.

Knocking down PRDX2 suppresses NSCLC cell metastasis by EMT in vivo. (a) PRDX2-knockdown or control A549 cells were injected into tail vein. (b) HE staining of lung metastatic nodules of mice was performed. (c) The number of lung metastatic nodules of mice was calculated. (d) The expression of E-cadherin, Vimentin, and Slug in the control group and PRDX2-knockdown group was performed by immunofluorescence assay. Scale bar = 200 μm in (b), scale bar = 50 μm in (d), ∗P < 0.05, ∗∗P < 0.01; ∗∗∗P < 0.001.