Table 3.

Effect of G6PD-binding on parameters of the f_∞-V relationship

	n	c1	c0	V0.5, mV	k, mV
Cav1.2	13	0.05 (0.02)	0.99 (0.02)	−26.0 (0.9)	14.0 (0.9)
C-G6PD545	7	0.12 (0.03)****	0.96 (0.03)	−27.1 (1.6)	13.4 (1.7)
N-G6PD545	7	0.06 (0.04) ###	1.01 (0.05)	−31.1 (2.3)****,####	16.0 (2.7)*,##

Values are means (SD); n, number of experiments. G6PD, glucose-6-phosphate dehydrogenase; c₁, voltage-independent component; c₀, maximal availability; V_0.5, voltage to produce 50% inactivation of the voltage-dependent component; k, slope factor. Statistical comparison of the parameters was performed using one-way ANOVA, followed by Turkey’s multiple comparison test.

^*P < 0.05,

^****P < 0.0001, compared with control.

^##P < 0.01,

^###P < 0.001,

^####P < 0.0001, compared with C-G6PD.