Fig. 5.

RORγt⁺ regulatory T cells are induced following defined microbiota transplant. (A and B) The proportion of colon and ileum lamina propria RORγt⁺ Treg cells (of live CD4⁺FoxP3⁺ cells) in groups of mice colonized with each IBD donor alone or 3 wk following DMT with one of the five HD microbiotas. Red lines indicate the proportion of RORγt⁺ Treg cells induced by each HD alone. Plots show the mean and SE of each group of mice. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001 by ANOVA with Tukey correction.