Table 1.
Samples | Age | Race/ethnicity | Gender | Type of MS | Stage | Disease duration, y | p40, pg/mL | p402, pg/mL | IL-12, pg/mL |
MS-1 | 49 | White | Male | RR-MS | Relapse | 14 | 679 ± 50 | 2,650 ± 135 | 5.51 ± 0.22 |
MS-2 | 50 | White | Female | RR-MS | Relapse | 9 | 929 ± 14 | 2,380 ± 475 | 3.39 ± 0.18 |
MS-3 | 50 | White | Female | RR-MS | Relapse | 10 | 555 ± 232 | 1,613 ± 133 | 10.08 ± 0.18 |
MS-4 | 51 | White | Female | RR-MS | Relapse | 7 | 755 ± 127 | 1,430 ± 285 | 7.37 ± 0.098 |
MS-5 | 53 | White | Male | RR-MS | Relapse | 6 | 514 ± 143 | 1,880 ± 140 | 4.66 ± 0.15 |
MS-6 | 56 | White | Female | RR-MS | Relapse | 12 | 614 ± 73 | 1,366 ± 143 | 11.61 ± 0.32 |
MS-7 | 50 | White | Male | RR-MS | Relapse | 5 | 555 ± 217 | 2,000 ± 60 | 6.27 ± 0.145 |
MS-8 | 51 | White | Male | RR-MS | Relapse | 15 | 250 ± 160 | 600 ± 185 | 8.22 ± 0.26 |
MS-9 | 29 | White | Female | RR-MS | Relapse | 3 | 190 ± 246 | 1,330 ± 90 | 3.31 ± 0.32 |
MS-10 | 49 | White | Male | RR-MS | Relapse | 7 | 210 ± 360 | 2,120 ± 660 | 8.56 ± 0.085 |
Control-1 | 55 | White | Female | Healthy | Healthy | Healthy | 1,490 ± 742 | 2,148 ± 399 | 2.8 ± 0.147 |
Control-2 | 63 | White | Female | Healthy | Healthy | Healthy | 1,983 ± 903 | 1,983 ± 305 | 2.1 ± 0.049 |
Control-3 | 61 | White | Female | Healthy | Healthy | Healthy | 1,326 ± 451 | 1,326 ± 113 | 0.73 ± 0.097 |
Control-4 | 70 | White | Male | Healthy | Healthy | Healthy | 1,140 ± 432 | 610 ± 80 | 0.96 ± 0.19 |
Control-5 | 38 | White | Female | Healthy | Healthy | Healthy | 1,856 ± 541 | 1,765 ± 247 | 3.5 ± 0.195 |
Control-6 | 61 | White | Male | Healthy | Healthy | Healthy | 1,729 ± 288 | 553 ± 76 | 2.17 ± 0.097 |
Control-7 | 63 | White | Male | Healthy | Healthy | Healthy | 1,060 ± 32 | 895 ± 272 | 7.26 ± 0.097 |
Control-8 | 38 | White | Female | Healthy | Healthy | Healthy | 1,018 ± 118 | 185 ± 27 | 9.49 ± 0.424 |
Control-9 | 63 | White | Male | Healthy | Healthy | Healthy | 1,779 ± 217 | 520 ± 190 | 4.49 ± 0.611 |
Control-10 | 32 | White | Female | Healthy | Healthy | Healthy | 863 ± 116 | 1,991 ± 435 | 4.63 ± 0.245 |
Serum samples of MS patients were obtained from the MS Clinic of the Rush University Medical Center. Serum samples from control subjects were obtained from Discovery Life Sciences (Los Osos, CA). Controls are healthy individuals without significant medical history. Each sample was analyzed for p40, p402, and IL-12 three times by ELISA. MS, multiple sclerosis; RR-MS, relapsing–remitting MS.