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. 2020 Aug 18;117(35):21512–21518. doi: 10.1073/pnas.2011249117

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Fig. 3. — IgG reactivity in B cell supernatants, second cohort. (A) Heatmap of antibody reactivity (in MFI) against 40 myelin antigens identified as significantly different between ELISpot-neg vs. ELISpot-pos B cell supernatants in SAM analysis (Top), nonmyelin controls (Middle), and positive control (Bottom). (B) Venn diagram indicating the number of overlapping significant antigens among the comparisons of ELISpot-neg vs. ELISpot-pos (supernatants, cohort 1) (orange), ELISpot-neg vs. ELISpot-pos (supernatants, cohort 2) (green), and HC/OND vs. MS (plasma) (blue).