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. 2020 Aug 17;117(35):21804–21812. doi: 10.1073/pnas.1921890117

Fig. 5.

Fig. 5.

A majority of central carbon metabolic enzymes retain their allocation when cells are growing at a faster rate in rich medium. (A) Comparison of average summed allocation, with SD, of quantified enzymes in glycolysis between cells cultivated in rich medium versus minimal medium (n = 3 for anaerobic and n = 2 for aerobic conditions). Highlighting the two most abundant enzymes. (B) Comparison of average summed allocation, with SD, of quantified enzymes in the TCA-cycle between cells cultivated in rich medium versus minimal medium (n = 3 for anaerobic and n = 2 for aerobic conditions). Highlighting significantly down-regulated enzymes and Aco1p, which showed the highest abundance. (C) Average summed allocation, with SD, of enzymes in glycolysis, based on Saccharomyces genome database pathway, see Dataset S1 (n = 3 for anaerobic and n = 2 for aerobic conditions). (D) Average summed allocation, with SD, of enzymes in the TCA-cycle, based on Saccharomyces genome database pathway, see SI Appendix (n = 3 for anaerobic and n = 2 for aerobic conditions. ***P < 1e-3.