Figure 3.

A Multi-Omic Approach for Genetic Improvement of Millet Species.

Integration of data gained from phenomics, genomics, epigenomics, transcriptomics, proteomics, and metabolomics would pinpoint candidate genes that could be manipulated using either transgene-based (overexpression/silencing) or genome-editing approaches to develop improved varieties. Integration of phenomic and genomic data either through genome-wide association studies or genomic selection will expedite breeding of improved varieties. Abbreviations: BS-Seq, bisulfite-sequencing; ChIP-Seq, chromatin immunoprecipitation and deep sequencing; GS, genomic selection; GWAS, genome-wide association studies; MeDIP-Seq, methylated DNA immunoprecipitation and deep sequencing.