Table 1.
Summarised statistical data regarding the comparison between suicide victims (n = 23) and controls (n = 25)
| Intergroup comparisons | Sex | Age (year) | PMI (h) | BAC (g/l) | AgNOR area cum all | AgNOR area cum males | AgNOR area cum females | AgNOR area right ACv layer V |
|---|---|---|---|---|---|---|---|---|
| Suicide victims | ||||||||
| Ratio/median (q1, q3) | 17 m/6f | 41.5 (28.5, 57.5) | 24 (24, 39) | 0.00 (0.00, 0.00) | 6.914 (6.228, 7.781) | 6.698 (6.040, 7.448) | 7.558 (6.895, 8.997) | 6.845 (6.148, 7.515) |
| Controls | ||||||||
| Ratio/median (q1, q3) | 21 m/4f | 57 (28, 61) | 24 (15, 30) | 0.00 (0.00, 0.00) | 7.212 (6.452, 8.418) | 7.170 (6.406, 8.333) | 7.744 (6.849, 8.992) | 7.734 (7.064, 8.368) |
| Statistics | ||||||||
| Test | χ2-test | U | U | U | GCD | GCD | GCD | U |
| Characteristic value | χ2 = 0.610 | Z = 0.890 | Z = − 0.790 | Z = 0.420 | Wald statistic = 33.87 | Wald statistic = 43.31 | Wald statistic = 0.03 | Z = 2.270 |
| P value | 0.435 | 0.373 | 0.429 | 0.675 | 0.00000000589 | 0.0000000000468 | 0.866 | 0.0232 |
PMI—postmortem interval, BAC—blood alcohol concentration, cum—cumulated results from layers III and V in all analysed regions of interest (ROIs), ACv—anterior cingulate cortex, ventral part, f—female, m—male, q1 and q3—quartile 1 and 3; GCD—general customs design procedure (in generalized linear/nonlinear models of data analysis software system STATISTICA). (See Supplementary Table 1 for the detailed values of confounding variables and AgNOR parameters in the right ACv layer V, i.e. the only ROI where the significant difference in AgNOR area in pyramidal neurons was found between compared groups.)