Table 1.
Patient | Sex | Age | PD duration | Comorbidities | PD Therapy | Institutionalization | COVID-19 symptoms | Worsening of PD | Change of PD therapy | Outcome |
---|---|---|---|---|---|---|---|---|---|---|
1 | F | 64 | 5 | Hypertension | Levodopa/carbidopa, Pramipexole |
No | Fever, Asthenia, Muscle pain | No | No | Recovery |
2 | M | 77 | 20 | Lung neoplasm (steady - in follow-up) | Levodopa/carbidopa | Yes | Fever, Asthenia, Cough, Dyspnea |
Yes: dysphagia and inability to stand | Yes: stopped after infection worsening | Death |
3 | F | 74 | 3 | Depression | Levodopa/benserazide, Pramipexole |
No | Fever, Asthenia, Muscle pain | Yes: worsening of rigidity and bradykinesia | No | Death |
4 | M | 63 | 21 | Diabetes in diet therapy | Melevodopa/carbidopa | Yes | Fever, Dyspnea |
Not assessable: patients already bedridden and fed with PEG | No | Death |
5 | F | 81 | 16 | Hypertension, hyperhomocysteinemia | Levodopa/carbidopa gel intestinal infusion, Entacapone | No | Fever, Dyspnea |
Yes: onset of disabling dyskinesia | No | Death |
6 | M | 79 | 15 | NA | Levodopa/carbidopa | NA | NA | NA | NA | Death |
7* | M | 80 | 5 | Hypertension, atrial fibrillation, benign prostatic hyperplasia | Levodopa/carbidopa | Yes | Fever, cough | Yes: in particular worsening of dysphagia | Yes: increase in levodopa dose | Recovery |
8 | M | NA | NA | NA | NA | NA | NA | NA | NA | Death |
PEG: percutaneous endoscopic gastrostomy.
NA: information not available.
*The patient reported some atypical parkinsonian symptoms/signs.
Caregivers of patients #6 and #8 did not accept to disclose further information, except those reported in the Table.