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. 2020 Aug 1;59(15):1819–1826. doi: 10.2169/internalmedicine.4458-20

Figure 3.

Figure 3.

The inflammatory cytokine levels of CTEPH patients and IPAH patients compared to the control group (patients cured from acute PTE without evidence of pulmonary hypertension). We measured the serum levels of TNF-α and IL-6 and the plasma level of pentraxin3 (PTX3) and P-selectin. The TNF-α, PTX3 and P-selectin levels in the CTEPH group were higher than in the control group [TNF-α; 2.63 (1.93-3.03) and 2.09 (1.69-2.27) pg/mL, PTX3; 4.10 (2.81-5.20) and 1.62 (1.56-2.04) ng/mL, P-selectin; 90.0 (66.9-108.1) and 52.1 (38.3-60.2) ng/mL in the CTEPH and control groups, respectively]. Some CTEPH patients had high IL-6 levels; however, there were no significant differences in the IL-6 levels according to a one-way ANOVA. The plasma PTX3 and P-selectin levels were also elevated in the IPAH group, although the TNF-α and IL-6 levels did not differ to a statistically significant extent. *, p<0.05; **, p<0.01.