Table 1.
The Basic Characteristics of the Patients.
| CTEPH n=41 | IPAH n=12 | p value | ||||
|---|---|---|---|---|---|---|
| Age (years) | 68 (55-73) | 50 (40-60) | 0.002‡ | |||
| Sex (M: F) | 18: 23 | 2: 10 | 0.086 | |||
| Body mass index (kg/m2) | 22.7 (20.4-25.4) | 21.5 (19.6-23.8) | 0.172 | |||
| Epworth sleepiness scale | 4.0±2.8 | 6.1±4.9 | 0.121 | |||
| Systolic blood pressure | 123.0±21.9 | 99.7±12.7 | 0.001‡ | |||
| Diastolic blood pressure | 70.0±12.4 | 61.4±10.2 | 0.033 | |||
| Treatment, N (%) | ||||||
| PH-specific therapy | 13 (31.7) | 11 (91.6) | <0.001‡ | |||
| Long-term oxygen | 30 (73.1) | 7 (58.3) | 0.324 | |||
| Pulmonary hemodynamics | ||||||
| mPAP (mmHg) | 41.7±12.8 | 35.0±10.2 | 0.106 | |||
| RAP (mmHg) | 5.4±3.1 | 5.0±3.6 | 0.674 | |||
| PVR (dyne·sec·cm-5) | 670 (403-882) | 412 (230-651) | 0.154 | |||
| Cardiac index (L/min/m2) | 2.46±0.37 | 2.85±0.66 | 0.012† | |||
| 6MWD(m) | 372.5±94.1 | 498.9±119.7 | <0.001‡ | |||
| BNP (pg/mL) | 72.9 (28.9-750) | 16.4 (8.2-84.6) | 0.015† | |||
| WHO-FC (I:II:III:IV) | 0:30:11:0 | 0:9:3:0 | 0.899 |
mPAP: mean pulmonary artery pressure, RAP: right atrial pressure, PVR: pulmonary vascular resistance, PaO2: arterial oxygen tension, PvO2: mixed venous oxygen tension, 6MWD: 6 minutes walking distance, BNP: brain natriuretic peptide. †, p<0.05; ‡, p<0.01