Table 2. Laboratory findings of old tree shrews infected with SARS-CoV-2.
| Parameter | Before inoculation (7/7, 100%) | After inoculation | |||||
| Total (7/7, 100%) | P-valuea | 3 dpi (2/7, 28%) | 5 dpi (2/7, 28%) | 7 dpi (2/7, 28%) | 14 dpi (1/7, 14%) | ||
|
a: P-values indicate differences before and after inoculation (total). P<0.05 was considered statistically significant. Data are means±SD (Test No./ Total No., %). Paired Student’s t test.
BUN: Blood urea nitrogen, TP: Total protein, ALB: Albumin, ALT: Alanine aminotransferase, AST: Aspartate aminotransferase. | |||||||
| White blood cell count (×109/L) | 1.45±0.53 | 3.12±2.25 | 0.0754 | 0.80±0.28 | 6.05±0.49 | 2.75±1.34 | 2.90 |
| Lymphocyte count (×109/L) | 0.45±0.26 | 1.67±1.68 | 0.1101 | 0.65±0.49 | 3.2±2.26 | 1.85±0.21 | 0.30 |
| Monocyte count (×109/L) | 0.21±0.07 | 0.20±0.16 | 0.8347 | 0.05±0.07 | 0.35±0.21 | 0.25±0.07 | 0.10 |
| Granulocyte count (×109/L) | 0.77±0.31 | 1.014±0.95 | 0.5320 | 0.50±0.28 | 0.50±0. 28 | 1.05±0.49 | 3.00 |
| Lymphocyte percentage (%) | 30.77±11.78 | 46.47±19.90 | 0.0977 | 44±8.34 | 56.80±37.34 | 51.2±3.11 | 22.30 |
| Monocyte percentage (%) | 16.53±4.19 | 8.41±2.52 | 0.0009 | 8.75±1.62 | 5.70±2.82 | 9.10±0.42 | 11.80 |
| Granulocyte percentage) (%) | 50.01±7.85 | 47.23±22.05 | 0.7583 | 54.25±16.62 | 47.9±49.21 | 39.70±2.68 | 46.90 |
| BUN (mg/dL) | 19.83±5.44 | 31.29±11.51 | 0.0087 | 36.50±6.36 | 43.00±4.24 | 21.5±3.53 | 17.00 |
| TP (g/dL) | 6.42±0.36 | 5.74±0.79 | 0.0200 | 5.45±1.06 | 5.55±0.92 | 6.50±0.28 | 5.20 |
| ALB (g/dL) | 3.26±0.35 | 2.50±0.55 | 0.0017 | 2.40±0.85 | 2.35±0.49 | 2.95±0.49 | 2.10 |
| Globulin (g/dL) | 3.13±0.21 | 3.25±0.29 | 0.3080 | 3.05±0.21 | 3.2±0.42 | 3.55±.021 | 3.20 |
| ALT (U/L) | 202.40±77.66 | 180.90±122.70 | 0.6428 | 187.00±86.27 | 115.50±33.23 | 264.50±238.30 | 132.00 |
| AST (U/L) | 229.00±31.97 | 361.30±316.20 | 0.1606 | 192.00±42.43 | 271.00±183.80 | 657.50±556.50 | 288.00 |