Table 6. Basic situation of common breast cancer transgenic mouse models.

Promoter	Transgene	Primary tumor		Metastasis			Pathology	References
		Latency	Incidence (%)	Incidence (%)	Latency	Metastatic site
AC: Adenocarcinoma; IDC: Invasive ductal carcinoma; d: Day; w: Week; m: Month.
MMTV-LTR	TGFα	6–13 m	40				AC	Halter et al., 1992; Matsui et al., 1990
	Wild-type-ErbB-2 (HER2,Neu)	7 m	100	72	8 m	Lung	AC	Guy et al., 1992b
	H-ras	5 w–6 m					AC	Sinn et al., 1987
	c-rel	19.9 m	31.6			Lung	AC	Romieu-Mourez et al., 2003
	PyMT	4–8 w	100	84–90	14 w	Lymph node, lung	IDC	Almholt et al., 2005
	c-Myc	4–8 m					AC	Stewart et al., 1984
	Cyclin D1	22 m	40					Wang et al., 1994
	Wnt-1	6 m	50			Lymph node, lung	AC	Li et al., 2000; Tsukamoto et al., 1988
WAP	TGFα	6–12 m	100				AC	Rose-Hellekant & Sandgren, 2000b; Sandgren et al., 1995
	Ras	24 w	100	14		Lung	AC	Nielsen et al., 1991
	c-Myc	5–10 m	100	20		Lung	AC	Rose-Hellekant & Sandgren, 2000a
	SV40	8–9 m					AC	Li et al., 1996; Santarelli et al., 1996
C(3)1	SV40	16 w	100	15		Lung	IDC	Green et al., 2000