Table 2.

Preoperative and postoperative static changes in glycaemic measures

Measurement	Preoperative	1 month	P value*	6 months	P value†
A1C (mmol/mol)	57.0 [46.0–89.3]	46.0 [38.5–56.0]	< 0.001	40.0 [36.0–49.0]	< 0.001
A1C (%)	7.4 [6.4–10.3]	6.3 [5.6–7.3]	< 0.001	5.8 [5.4–6.6]	< 0.001
Fasting glucose (mmol/L)	7.1 [5.9–11.7]	5.6 [4.6–6.8]	< 0.001	5.2 [4.5–5.8]	< 0.001
2-h glucose (mmol/L)	13.4 [9.2–18.4]	8.8 [5.2–12.7]	< 0.001	5.8 [4.2–9.4]	< 0.001
Fasting insulin (mU/L)	21.8 [13.7–29.5]	12.0 [8.9–19.3]	< 0.001	9.0 [5.4–14.1]	< 0.001
2-h insulin (mU/L)	52.8 [27.4–102.4]	47.1 [27.7–122.6]	0.210	29.7 [16.2–56.9]	0.010
Fasting C-peptide (pmol/mL)	4.0 [3.5–5.2]	3.6 [2.7–4.8]	0.002	2.8 [2.0–3.9]	< 0.001
2-h C-peptide (pmol/mL)	8.7 [6.5–11.2]	10.0 [7.7–12.5]	0.058	8.7 [5.9–11.5]	0.868
HOMA-IR	3.1 [1.9–4.1]	1.6 [1.2–2.6]	< 0.001	1.3 [0.8–1.9]	< 0.001
HOMA-%B	90.1 [36.2–131.6]	110.0 [73.0–147.0]	0.343	99.5 [81.0–150.2]	0.288
HOMA-%S	32.4 [24.5–52.3]	62.3 [39.0–81.7]	< 0.001	75.5 [52.3–121.0]	< 0.001

Median and interquartile ranges shown

^*P value comparing preoperative with 1 month

^†P value comparing preoperative with 6 months

Significant values are in bold. A1C = glycated haemoglobin. HOMA-IR = homeostatic model assessment insulin resistance. HOMA-%S = homeostatic model assessment insulin sensitivity. HOMA-%B = homeostatic model assessment β cell function