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. 2020 Sep 6;6:81. doi: 10.1038/s41420-020-00315-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a MCF7, MDA-MB-231, HCC1569, and BT549 breast cancer cells were treated with various concentration of HNK (5.0, 10.0, 15.0, 20.0, 25.0, and 30.0µM) in combination with 25µM of CQ for 24h. Cells were subjected to MTT assay and combination index values were calculated using CompuSyn software. CI < 1 shows synergism, CI = 1 shows additivity and CI > 1 shows antagonism. b Table shows combination index for different concentrations of HNK and CQ.