Diabetes leads to a worse prognosis after ischemic stroke. A Neurological deficit scores in nonDM-Stroke and DM-Stroke mice at 24 h and 7, 14, 21, and 28 days (n = 9 per group). B Mortality until day 28 in nonDM-Stroke (n = 40) and DM-Stroke (n = 53) mice. nonDM-Stroke, non-diabetic stroke group; DM-Stroke, diabetic stroke group. Data are expressed as the mean ± SD. *P < 0.05; **P < 0.01 (Student’s t-test in A and log-rank test in B).