Table 1.
Antibacterial activity of selected compounds isolated from C. incisa leaves.
| Compoundsa | Strains of MDR bacteriab. MIC (μg/mL) |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| MRSA | LRSE | VREF | CRAB | ECPB | PARC | KPNDM-1+ | KPPB | KPRO | |
| (2) | >200 | 200 | 200 | 200 | >200 | 200 | 200 | >200 | 200 |
| (2Ac) | >200 | 200 | 200 | 100 | >200 | 200 | 200 | >200 | >200 |
| (3) | >200 | 200 | 200 | 200 | >200 | 200 | >200 | >200 | 200 |
| (3Ac) | >200 | >200 | 200 | 200 | >200 | 200 | >200 | >200 | 200 |
| (4) | >200 | >200 | >200 | >200 | >200 | 100 | >200 | >200 | >200 |
| (5) | >200 | >200 | >200 | >200 | >200 | 100 | >200 | >200 | >200 |
| (5Ac) | >200 | >200 | >200 | 200 | >200 | 200 | 200 | 200 | 200 |
| levofloxacin | 12.5 | 6.25 | 12.5 | 12.5 | 12.5 | 12.5 | >50 | >50 | >50 |
2,3-dihydroxypropyl tetracosanoate (2); 3-(tetracosanoyloxy) propane-1,2-diyl diacetate (2Ac);β-sitosterol-D-glucopyranoside (3); β-sitosteryl β-D-tetraacetyl glucopyranoside (3Ac); α-amyrin-3-O-β-D-glucopyranoside (4); cerebrosides (5); acetylated cerebrosides (5Ac).
(MRSA) Methicillin-Resistant Staphylococcus aureus); (LRSE) Linezolid-resistant Staphylococcus epidermidis; (VREF) Vancomycin-resistant Enterococcus faecium; (CRAB) Carbapenems-resistant Acinetobacter baumannii; (ECPB) Escherichia coli producing ESBL; (PARC) Pseudomonas aeruginosa resistant to carbapenems; (KPNDM-1+) carbapenems-resistant Klebsiella pneumoniae NDM-1+; (KPPB) Klebsiella pneumoniae producer of ESBL; (KPOX) carbapenems-resistant Klebsiella pneumoniae (OXA 48-positive).