Fig. 2.

Vertebrate globins and their distribution. Schematic cladogram of the vertebrate globin repertoire. Notable differences in expression patterns are summarized on the right of each phylogenetic branch, including the selective loss of Hb and Mb in ray-finned fish subspecies or the selective duplication of Mb in ray-finned fish subspecies, and the duplications of Mb and GbE in lungfishes. Hb: hemoglobin, Mb: myoglobin, Ngb: neuroglobin, Cygb: cytoglobin, Adgb: androglobin, GbE: globin E, GbX: globin X, GbY: globin Y.