2.
Baseline characteristics: presence versus absence of paroxysmal atrial fibrillation.
| Characteristic | Presence of paroxysmal AF | Absence of paroxysmal AF | ||||||
| (n = 67) | P-value* | P-value** | P-value# | (n = 206) | P-value* | P-value** | ||
| Data are presented as means ± SD or n (%). & Presented as median (interquartile range). *Refers to versus control group. **Refers to versus persistent AF. #Refers to versus absence of AF group. ACEIs: angiotensin-converting enzyme inhibitors; AF: atrial fibrillation; ARBs: angiotensin receptor blocking agents; BMI: body mass index; CCBs: calcium channel blockers; DBP: diastolic blood pressure; Hb: hemoglobin; HDL-c: high-density lipoprotein cholesterol; IVST: interventricular septum thickness; LAD: left atrial diameter; LDL-c: low-density lipoprotein cholesterol; LVEDD: left ventricular end diastolic diameter; LVEF: left ventricular ejection fraction; LVPWT: left ventricular posterior wall thickness; RDW: red cell distribution width; SBP: systolic blood pressure; TG: total cholesterol; WBC: white blood cell. | ||||||||
| Age, yrs | 57.1 ± 10.3 | 0.105 | 0.024 | 0.001 | 61.8 ± 10.6 | 0.001 | 0.468 | |
| Male | 58 (86.6%) | 0.006 | 0.438 | 0.001 | 119 (57.8%) | 0.145 | 0.001 | |
| Smoking | 22 (32.8%) | 0.434 | 0.906 | 0.596 | 75 (36.4%) | 0.678 | 0.680 | |
| Duration of hypertension, yrs | 8 (5-10) & | 0.067 | 0.157 | 0.317 | 7 (6-11) & | 0.001 | 0.471 | |
| BMI, kg/m2 | 24.7 ± 1.9 | 0.217 | 0.219 | 0.372 | 24.4 ± 2.4 | 0.559 | 0.021 | |
| Office heart rate, beats/min | 88.4 ± 15.4 | 0.001 | 0.212 | 0.001 | 73.6 ± 15.9 | 0.675 | 0.001 | |
| Office SBP, mmHg | 144.3 ± 7.0 | 0.860 | 0.033 | 0.533 | 144.8 ± 5.5 | 0.163 | 0.021 | |
| Office DBP, mmHg | 88.2 ± 9.2 | 0.860 | 0.010 | 0.156 | 90.2 ± 10.0 | 0.202 | 0.161 | |
| WBC, ×109/L | 5.9 ± 1.4 | 0.032 | 0.208 | 0.189 | 5.4 ± 1.8 | 0.001 | 0.854 | |
| Hb, g/L | 145.1 ± 15.8 | 0.045 | 0.080 | 0.048 | 140.6 ± 16.2 | 0.681 | 0.001 | |
| RDW, % | 13.0 ± 0.6 | 0.001 | 0.533 | 0.001 | 12.5 ± 0.9 | 0.262 | 0.001 | |
| Creatinine, μmol/L | 82.1 ± 13.4 | 0.029 | 0.102 | 0.061 | 78.0 ± 16.7 | 0.820 | 0.001 | |
| TG, mmol/L | 4.9 ± 0.5 | 0.180 | 0.503 | 0.881 | 4.9 ± 0.5 | 0.170 | 0.355 | |
| HDL-c, mmol/L | 1.4 ± 0.2 | 0.016 | 0.007 | 0.677 | 1.4 ± 0.2 | 0.003 | 0.001 | |
| LDL-c, mmol/L | 3.0 ± 0.4 | 0.714 | 0.386 | 0.169 | 3.1 ± 0.4 | 0.339 | 0.735 | |
| Triglycerides, mmol/L | 1.9 ± 0.4 | 0.002 | 0.001 | 0.001 | 1.7 ± 0.3 | 0.093 | 0.868 | |
| Fasting glucose, mmol/L | 4.8 ± 0.7 | 0.673 | 0.246 | 0.633 | 4.8 ± 0.6 | 0.288 | 0.335 | |
| Na+, mmol/L | 141.2 ± 2.5 | 0.075 | 0.579 | 0.532 | 141.4 ± 2.4 | 0.114 | 0.168 | |
| K+, mmol/L | 4.0 ± 0.3 | 0.884 | 0.012 | 0.669 | 4.0 ± 0.3 | 0.510 | 0.001 | |
| LAD, mm | 40.1 ± 4.7 | 0.001 | 0.001 | 0.004 | 38.0 ± 5.4 | 0.001 | 0.001 | |
| LVEDD, mm | 48.6 ± 4.6 | 0.015 | 0.839 | 0.107 | 47.6 ± 4.7 | 0.227 | 0.130 | |
| LVPWT, mm | 11.4 ± 1.0 | 0.001 | 0.223 | 0.230 | 11.2 ± 1.4 | 0.001 | 0.012 | |
| IVST, mm | 11.4 ± 1.8 | 0.001 | 0.035 | 0.777 | 11.5 ± 1.5 | 0.001 | 0.008 | |
| LVEF, % | 62.4 ± 4.6 | 0.530 | 0.034 | 0.479 | 62.9 ± 4.2 | 0.802 | 0.001 | |
| ACEIs/ARBs | 46 (68.7%) | 0.837 | 0.013 | 0.130 | 120 (58.3%) | 0.167 | 0.124 | |
| Statins | 20 (29.9%) | 0.001 | 0.106 | 0.543 | 55 (26.7%) | 0.768 | 0.009 | |
| Beta-blockers | 28 (41.8%) | 0.079 | 0.977 | 0.234 | 80 (38.8%) | 0.085 | 0.677 | |
| Diuretics | 11 (16.4%) | 0.484 | 0.586 | 0.638 | 29 (14.1%) | 0.673 | 0.813 | |
| CCBs | 31 (46.3%) | 0.460 | 0.001 | 0.471 | 85 (41.3%) | 0.874 | 0.001 | |
| Propafenone | 20 (29.9%) | - | 0.735 | 0.616 | 55 (26.7%) | - | 0.276 | |
| Amiodarone | 25 (37.3%) | - | 0.906 | 0.097 | 55 (26.7%) | - | 0.112 | |
| Digoxin | 11 (16.4%) | - | 0.723 | 0.638 | 29 (14.1%) | - | 0.964 | |
| Aspirin | 34 (50.7%) | 0.326 | 0.747 | 0.970 | 104 (50.5%) | 0.232 | 0.716 | |
| Anticoagulation drugs | 7 (10.4%) | - | 0.091 | 0.301 | 32 (15.5%) | - | 0.295 | |
| Warfarin | 4 (6.0%) | - | 0.156 | 0.155 | 25 (12.1%) | - | 0.847 | |
| Dabigatran/Rivaroxaban | 3 (4.5%) | - | 0.277 | 0.683 | 7 (3.4%) | - | 0.049 | |