Table 2. Clinical outcome of KD after 1, 3, and 6 months.
Clinical outcome | 1 montha (n=139) | 3 monthsb (n=129) | 6 monthsc (n=103) |
---|---|---|---|
Seizure reduction-responder, n (%) | 39 (28.0) | 71 (55.0)* | 70 (67.9)* |
Seizure free | 9 (6.5) | 17 (13.2)* | 24 (23.3)* |
>75% reduction | 12 (8.6) | 23 (17.8)* | 16 (15.5)* |
50–75% reduction | 18 (12.9) | 31 (24.0)* | 30 (29.1)* |
Seizure reduction non-responder, n (%) | 100 (72.0) | 58 (45.0)* | 33 (32.0)* |
<50% reduction | 49 (35.3) | 35 (27.1)* | 22 (21.4)* |
No change | 51 (36.7) | 23 (17.9)* | 11 (10.6)* |
Other clinical outcome | |||
Weight, medium (range, Kg) | – | – | 14.0 (1.5–59.7) |
Neurobehavioral improvement, n (%) | 67 (48.2) | – | – |
EEG improvement, n (%) | 59 (42.4) | – | – |
a, lost to follow-up: 7 patients; b, lost to follow-up: 10 patients; c, lost to follow-up: 36 patients. *, compared with efficacy at 1 month; P value <0.05. KD, ketogenic diet.