Table 2. Univariate analysis of OS and DFS in TCGA dataset.
Factor | OS | DFS | |||||
---|---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | ||
Age | 0.019 | 0.701 | |||||
<60 | 1 | 1 | |||||
≥60 | 1.545 | 1.074–2.222 | 1.082 | 0.724–1.617 | |||
Sex | 0.264 | 0.005 | |||||
Female | 1 | 1 | |||||
Male | 1.211 | 0.866–1.694 | 1.92 | 1.218–3.028 | |||
Stage | <0.001 | 0.017 | |||||
I | 1 | 1 | |||||
II | 1.494 | 0.776–2.879 | 1.998 | 0.953–4.187 | |||
III | 2.413 | 1.311–4.443 | 2.366 | 1.157–4.840 | |||
IV | 3.978 | 1.988–7.962 | 3.79 | 1.637–8.775 | |||
Histology | 0.005 | 0.198 | |||||
Adenocarcinoma | 1 | 1 | |||||
Mucinous | 0.246 | 0.078–0.776 | 0.377 | 0.119–1.195 | |||
Signet ring cell carcinoma | 2.333 | 1.184–4.598 | 1.825 | 0.738–4.516 | |||
Diffuse type | 0.85 | 0.55–1.032 | 0.994 | 0.613–1.613 | |||
Grade | 0.027 | 0.139 | |||||
G1/G2 | 1 | 1 | |||||
G3 | 1.461 | 1.045–2.043 | 1.353 | 0.907–2.018 | |||
CPT1A | 0.995 | 0.801–1.235 | 0.961 | 0.845 | 0.650–1.099 | 0.21 | |
CPT1B | 0.941 | 0.820–1.081 | 0.391 | 1.022 | 0.855–1.223 | 0.808 | |
CPT1C | 1.184 | 1.071–1.390 | <0.001 | 1.217 | 1.083–1.367 | <0.001 |
TCGA, The Cancer Genome Atlas; DFS, disease free survival; OS, overall survival.