Table 2. Univariate and multivariate analyses for OS.
| Variable | Univariate | Multivariate | |||
|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | ||
| Age | |||||
| 20–69 vs. 70+ | 0.68 (0.67–0.70) | <0.0001 | 0.76 (0.74–0.78) | <0.0001 | |
| Sex | |||||
| Female vs. male | 1.01 (0.95–1.07) | 0.7576 | 0.98 (0.95–1.00) | 0.0811 | |
| Race | |||||
| Others vs. Whites | 0.97 (0.94–1.01) | 0.1548 | 0.96 (0.92–0.99) | 0.0200 | |
| Institution | |||||
| Academic vs. nonacademic | 0.81 (0.79–0.83) | <0.0001 | 0.83(0.80–0.85) | <0.0001 | |
| Insurance | |||||
| Yes vs. no | 0.99 (0.91–1.08) | 0.8356 | 0.92 (0.84–1.01) | 0.0710 | |
| Charlson-Deyo score | |||||
| 0–1 vs. 2–3 | 0.72 (0.68–0.75) | <0.0001 | 0.80 (0.76–0.84) | <0.0001 | |
| Histology | |||||
| Others vs. adenocarcinoma | 0.73 (0.71–0.76) | <0.0001 | 0.64 (0.62–0.66) | <0.0001 | |
| Liver metastasis | |||||
| No vs. yes | 0.89 (0.86–0.92) | <0.0001 | 0.83 (0.80–0.86) | <0.0001 | |
| Lung metastasis | |||||
| No vs. yes | 0.85 (0.82–0.88) | <0.0001 | 0.83 (0.81–0.86) | <0.0001 | |
| Radiation | |||||
| Yes vs. no | 0.91 (0.86–0.97) | 0.0033 | 1.02 (0.96–1.09) | 0.4821 | |
| Chemotherapy | |||||
| Yes vs. no/unknown | 0.55 (0.53–0.56) | <0.0001 | 0.53 (0.51–0.54) | <0.0001 | |
| Primary location | |||||
| Pancreatic head vs. other | 0.97 (0.94–1.00) | 0.0396 | 0.97 (0.94–1.00) | 0.00394 | |
| Immunotherapy | |||||
| Yes vs. no/unknown | 0.60 (0.49–0.71) | <0.0001 | 0.69 (0.57–0.82) | <0.0001 | |
HR, hazard ratio; CI, confidence interval; OS, overall survival.