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. 2020 Aug;11(4):747–759. doi: 10.21037/jgo-20-59

Table 2. Subgroups analysis of OR and DC achievement in T + P group.

Characteristics OR DC
Yes (n=34) No (n=40) P value Yes (n=55) No (n=19) P value
Age, years 51.3±13.2 53.55±11.8 0.451 53.2±12.2 50.6±13.3 0.467
Gender 0.171 1.000
   Female 7 3 8 2
   Male 27 37 47 17
HBsAg 0.147 0.746
   Positive 25 35 45 15
   Negative 9 5 10 4
Cirrhosis 1.000 0.643
   Yes 31 37 51 17
   No 3 3 4 2
Child-Pugh grade 1.000 0.450
   A 33 39 54 18
   B 1 1 1 1
Portal vein invasion 0.057 0.785
   Yes 17 11 20 8
   No 17 29 35 11
Hepatic vein invasion 0.002 1.000
   Yes 13 3 12 4
   No 21 37 43 15
Largest tumor size 0.061 0.429
   <5 cm 13 25 30 8
   ≥5 cm 21 15 25 11
Tumor number 0.804 0.576
   <2 12 12 20 5
   ≥2 22 28 35 14
ECOG 0.138 0.054
   0–1 26 23 40 9
   2 8 17 15 10
BCLC stage 0.012 0.100
   A 3 12 14 1
   B 9 15 15 9
   C 22 13 26 9
AFP 0.815 0.788
   <20 ng/mL 15 16 24 7
   ≥20 ng/mL 19 24 31 12
WBC, 109/L 6.5±2.6 6.3±2.5 0.778 6.5±2.7 6.2±1.9 0.526
PLT, 109/L 152.9±85.3 172.6±68.7 0.283 162.4±67.3 166.8±101.8 0.864
ALB, g/L 44.2±4.4 45.2±4.5 0.300 45.2±4.5 43.47±4.1 0.141
TBIL, µmol/L 16.5±7.1 15.6±5.1 0.541 15.6±5.2 17.3±8.3 0.395
ALT, U/L 39.3±20.7 41.6±24.5 0.670 39.9±22.2 42.4±24.6 0.703
AST, U/L 42.6±21.8 40.4±23.0 0.675 41.7±23.6 40.7±18.9 0.862

OR, objective response; DC, disease control; T + P, tegafur plus pirarubicin; HBsAg, hepatitis B virus surface antigen; ECOG, Eastern Cooperative Oncology Group; BCLC, Barcelona Clinic Liver Cancer; AFP, alpha fetoprotein; WBC, white blood cell; PLT, platelet; ALB, albumin; TBIL, total bilirubin; ALT, alanine aminotransferase; AST, aspartate aminotransferase.