Table 3. Age-period-cohort effect analysis results of TC incidence in in selected East Asian countries.
| Effect | Relative risk (95% CI) | |||||
|---|---|---|---|---|---|---|
| Male in China | Female in China | Male in Japan | Female in Japan | Male in Korea | Female in Korea | |
| Age, years | ||||||
| 20–24 | 0.17 (0.09 to 0.29) | 0.33 (0.26 to 0.43) | 0.53 (0.28 to 1.01) | 0.37 (0.27 to 0.52) | 0.23 (0.15 to 0.35) | 0.27 (0.22 to 0.32) |
| 25–29 | 0.60 (0.56 to 0.65) | 0.79 (0.76 to 0.82) | 1.02 (1.00 to 1.04) | 0.65 (0.60 to 0.71) | 0.52 (0.47 to 0.57) | 0.58 (0.55 to 0.60) |
| 30–34 | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| 35–39 | 1.57 (1.55 to 1.59) | 1.15 (1.14 to 1.17) | 0.98 (0.98 to 0.99) | 1.32 (1.28 to 1.35) | 1.53 (1.49 to 1.57) | 1.41 (1.39 to 1.43) |
| 40–44 | 2.15 (2.09 to 2.21) | 1.38 (1.36 to 1.41) | 2.04 (1.67 to 2.50) | 1.84 (1.72 to 1.96) | 2.33 (2.27 to 2.39) | 1.99 (1.95 to 2.03) |
| 45–49 | 2.84 (2.74 to 2.94) | 1.62 (1.60 to 1.65) | 2.02 (1.65 to 2.48) | 1.88 (1.73 to 2.04) | 3.06 (2.97 to 3.14) | 2.51 (2.46 to 2.57) |
| 50–54 | 2.55 (2.46 to 2.64) | 1.86 (1.82 to 1.91) | 2.75 (2.08 to 3.65) | 2.25 (2.02 to 2.51) | 3.28 (3.17 to 3.40) | 3.07 (2.98 to 3.15) |
| 55–59 | 3.36 (3.04 to 3.71) | 1.98 (1.93 to 2.03) | 3.33 (2.34 to 4.73) | 2.31 (2.02 to 2.65) | 3.53 (3.34 to 3.73) | 2.91 (2.83 to 2.99) |
| 60–64 | 2.67 (2.38 to 2.99) | 1.86 (1.81 to 1.91) | 3.08 (2.04 to 4.66) | 2.30 (1.95 to 2.72) | 3.39 (3.14 to 3.67) | 2.76 (2.68 to 2.85) |
| 65–69 | 2.40 (2.03 to 2.82) | 1.45 (1.42 to 1.49) | 3.68 (2.30 to 5.88) | 2.35 (1.94 to 2.85) | 2.79 (2.52 to 3.10) | 2.08 (2.02 to 2.14) |
| 70–74 | 1.83 (1.50 to 2.23) | 1.12 (1.10 to 1.13) | 3.96 (2.41 to 6.49) | 2.11 (1.74 to 2.56) | 1.57 (1.42 to 1.73) | 1.36 (1.34 to 1.39) |
| 75–79 | 0.97 (0.84 to 1.11) | 0.76 (0.76 to 0.76) | 3.62 (2.25 to 5.83) | 1.90 (1.59 to 2.28) | 1.09 (0.99 to 1.20) | 0.74 (0.74 to 0.75) |
| 80–84 | 0.52 (0.50 to 0.55) | 0.48 (0.45 to 0.52) | 3.10 (2.13 to 4.52) | 1.55 (1.36 to 1.76) | 0.62 (0.60 to 0.64) | 0.29 (0.27 to 0.31) |
| Period | ||||||
| 1997 | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| 2002 | 1.48 (1.42 to 1.54) | 1.23 (1.22 to 1.24) | 0.94 (0.91 to 0.97) | 0.96 (0.95 to 0.97) | 1.72 (1.64 to 1.79) | 1.61 (1.59 to 1.64) |
| 2007 | 2.20 (2.08 to 2.32) | 1.84 (1.79 to 1.90) | 1.77 (1.66 to 1.87) | 1.62 (1.58 to 1.66) | 6.00 (5.48 to 6.57) | 4.97 (4.78 to 5.17) |
| 2012 | 4.31 (3.94 to 4.71) | 3.53 (3.37 to 3.71) | 2.19 (2.10 to 2.29) | 1.94 (1.90 to 1.99) | 13.55 (12.16 to 15.11) | 9.78 (9.34 to 10.24) |
| Birth cohort | ||||||
| 1912–1916 | 8.90 (5.66 to 13.99) | 2.41 (1.58 to 3.68) | 1.25 (0.94 to 1.65) | 1.49 (1.19 to 1.86) | 5.26 (2.97 to 9.33) | 3.29 (2.16 to 4.99) |
| 1917–1921 | 6.91 (6.29 to 7.61) | 2.63 (2.30 to 3.02) | 2.12 (2.04 to 2.21) | 1.94 (1.89 to 2.00) | 6.39 (5.44 to 7.50) | 4.12 (3.63 to 4.69) |
| 1922–1926 | 5.04 (4.67 to 5.44) | 1.86 (1.77 to 1.96) | 1.21 (1.07 to 1.36) | 1.35 (1.39 to 1.30) | 3.63 (3.50 to 3.76) | 1.72 (1.58 to 1.87) |
| 1927–1931 | 2.25 (2.04 to 2.49) | 1.11 (1.10 to 1.13) | 1.02 (0.84 to 1.24) | 1.18 (1.08 to 1.28) | 2.32 (2.21 to 2.43) | 1.18 (1.14 to 1.22) |
| 1932–1936 | 1.46 (1.35 to 1.58) | 1.05 (1.04 to 1.05) | 1.22 (1.00 to 1.50) | 1.05 (0.97 to 1.14) | 1.70 (1.62 to 1.80) | 1.10 (1.09 to 1.11) |
| 1937–1941 | 1.64 (1.47 to 1.84) | 0.85 (0.85 to 0.86) | 0.77 (0.69 to 0.87) | 0.96 (0.91 to 1.01) | 1.32 (1.27 to 1.37) | 0.92 (0.91 to 0.93) |
| 1942–1946 | 1.23 (1.17 to 1.29) | 1.06 (1.05 to 1.06) | 0.89 (0.84 to 0.95) | 1.00 (0.98 to 1.04) | 1.10 (1.08 to 1.13) | 1.00 (1.00 to 1.00) |
| 1947–1951 | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| 1952–1956 | 1.06 (1.05 to 1.07) | 1.20 (1.19 to 1.20) | 0.74 (0.69 to 0.81) | 0.81 (0.79 to 0.84) | 1.08 (1.06 to 1.09) | 1.06 (1.06 to 1.06) |
| 1957–1961 | 1.09 (1.05 to 1.14) | 1.26 (1.25 to 1.28) | 0.78 (0.67 to 0.91) | 0.73 (0.68 to 0.78) | 1.11 (1.09 to 1.14) | 1.13 (1.13 to 1.13) |
| 1962–1966 | 1.10 (1.06 to 1.16) | 1.16 (1.15 to 1.16) | 0.73 (0.60 to 0.88) | 0.80 (0.74 to 0.86) | 1.25 (1.22 to 1.28) | 1.19 (1.19 to 1.19) |
| 1967–1971 | 1.50 (1.46 to 1.53) | 1.25 (1.23 to 1.27) | 0.84 (0.70 to 1.00) | 0.68 (0.62 to 0.75) | 1.65 (1.63 to 1.67) | 1.25 (1.25 to 1.25) |
| 1972–1976 | 1.70 (1.63 to 1.78) | 1.34 (1.32 to 1.36) | 0.36 (0.22 to 0.59) | 0.63 (0.55 to 0.72) | 2.36 (2.35 to 2.36) | 1.50 (1.50 to 1.51) |
| 1977–1981 | 3.12 (2.98 to 3.26) | 1.28 (1.25 to 1.32) | 0.61 (0.42 to 0.88) | 0.71 (0.59 to 0.86) | 2.18 (2.10 to 2.26) | 1.50 (1.47 to 1.52) |
| 1982–1986 | 4.59 (3.84 to 5.47) | 1.44 (1.30 to 1.60) | 0.42 (0.21 to 0.85) | 0.75 (0.53 to 1.05) | 2.38 (2.02 to 2.81) | 1.49 (1.38 to 1.60) |
| 1987–1992 | 3.50 (1.17 to 10.50) | 1.46 (0.89 to 2.38) | 0.16 (0.01 to 3.35) | 0.98 (0.43 to 2.21) | 1.86 (0.94 to 3.69) | 1.07 (0.78 to 1.48) |