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. 2020 Aug;8(15):929. doi: 10.21037/atm-20-1054

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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eUb promoted the metastasis of hepatoma cells in the tumor-bearing model. The mice were intraperitoneally injected with eUb (Ub group: 1.6 µg/mL) or normal saline (CON, control group) after Hepa1-6-luciferase cells were injected into the tail vein of mice. (A,B) Tumor metastasis was detected by bioluminescent signal and H&E staining, and the arrows indicated the tumor metastases. (C) The lung tissues of the mice were harvested to detect the proteins related to tumor metastasis through Western blot. GAPDH was used as a loading control. *, P<0.05. CON, control.