Table 1. Clinicopathological characteristics of GC patients with high and low PYCR1 protein expression.
| Clinical parameters | Total (n=90) | PYCR1 expression | χ2 | P | |
|---|---|---|---|---|---|
| Low (n=33) | High (n=57) | ||||
| Sex (male/female) | 61/29 | 21/12 | 40/17 | 0.409 | 0.522 |
| Age (<60/≥60 years) | 30/60 | 15/18 | 15/42 | 3.445 | 0.063 |
| Tumor size (<5/≥5 cm) | 34/56 | 15/18 | 19/38 | 1.306 | 0.253 |
| Histologic type | 0.006§ | ||||
| Tubular/papillary | 68 | 19 | 49 | – | |
| Mucinous | 9 | 7 | 2 | ||
| Signet-ring-cell and others‡ | 13 | 7 | 6 | ||
| Differentiation (well + moderate/poor) | 14/76 | 4/29 | 10/47 | 0.468 | 0.494 |
| Ki-67 Index (low/high)¶ | 52/38 | 26/7 | 26/31 | 9.428 | 0.002 |
| Invasion depth (T1 + 2/T3 + 4) | 15/75 | 8/25 | 7/50 | 2.153 | 0.142 |
| Lymph node metastasis (N0/N1–3) | 26/64 | 12/21 | 14/43 | 1.417 | 0.234 |
| Distant metastasis (M0/M1) | 82/8 | 31/2 | 51/6 | 0.111 | 0.739† |
| Stage (I + II/III + IV) | 39/41 | 21/12 | 18/39 | 8.747 | 0.003 |
Statistical analyses was performed by chi square test. †, continuity adjusted value for chi square test; ‡, other refers to one case of non-differentiated cancer; §, Fisher’s exact test; ¶, split by median value.