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. 2020 Aug;8(15):950. doi: 10.21037/atm-20-2901

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Pan-cancer analysis of RACGAP1. (A) The mRNA Level of RACGAP1 is significantly upregulated in 18 types of human cancer. (B) High expression of RACGAP1 was related to worse overall survival (OS) in 8 types of cancer. (C) RACGAP1 mRNA level is positively correlated with the E2F3 mRNA level in 11 types of cancer. (D) RACGAP1 mRNA level is significantly higher in E2F3 copy number gain tumor samples than E2F3 copy number not-gain tumor samples in 6 types of cancer. Error bars represent means ± SD. *, P<0.05; **, P<0.01; ***, P<0.001, the P values were calculated by Student’s t-test or long-rank test. ACC, adrenocortical carcinoma; BLCA, bladder urothelial carcinoma; BRCA, breast invasive carcinoma; CESC, cervical squamous cell carcinoma and endocervical adenocarcinoma; COAD, colon adenocarcinoma; DLBC, lymphoid neoplasm diffuse large B-cell lymphoma; GBM, glioblastoma multiforme; HNSC, head and neck squamous cell carcinoma; LGG, low grade glioma; LIHC, liver hepatocellular carcinoma; LUSC, lung squamous cell carcinoma; OV, ovarian serous cystadenocarcinoma; PAAD, pancreatic adenocarcinoma; READ, rectum adenocarcinoma; SARC, sarcoma; SKCM, skin cutaneous melanoma; STAD, stomach adenocarcinoma; THYM, thymoma; UCEC, uterine corpus endometrial carcinoma.