Table 1. Proportion of various histopathologic lesion in 44 BKPyVAN patients with glomerular involvement.
| Pathological features | N (%) |
|---|---|
| Glomerulitis | |
| g0 | 25 (56.8) |
| g1 | 19 (43.2) |
| Chronic transplant glomerulopathy | |
| cg 0 | 42 (95.5) |
| cg 1 | 1 (2.3) |
| cg 2 | 1 (2.3) |
| Crescents | 7 (15.9) |
| Peri-glomerular fibrosis | 29 (65.9) |
| Extent of SV40 large T antigen | |
| 1+ | 6 (13.6) |
| 2+ | 12 (27.3) |
| 3+ | 21 (47.7) |
| 4+ | 5 (11.4) |
| Tubulitis | |
| t1 | 25 (56.8) |
| t2 | 13 (29.5) |
| t3 | 6 (13.6) |
| Interstitial inflammation | |
| i0 | 9 (20.5) |
| i1 | 18 (40.9) |
| i2 | 10 (22.7) |
| i3 | 7 (15.9) |
| Tubular atrophy | |
| ct1 | 11 (25.0) |
| ct2 | 27 (61.4) |
| ct3 | 6 (13.6) |
| Interstitial fibrosis | |
| ci1 | 11 (25.0) |
| ci2 | 23 (52.3) |
| ci3 | 10 (22.7) |
| Peri-tubular capillaritis | |
| pct0 | 25 (56.8) |
| ptc1 | 17 (38.6) |
| ptc2 | 2 (4.5) |
| Endarteritis | 0 |
| BKPyVAN stage | |
| Stage A | 0 |
| Stage B1 | 8 (18.2) |
| Stage B2 | 11 (25.0) |
| Stage B3 | 20 (45.5) |
| Stage C | 5 (11.4) |
| CNI nephrotoxicity | 2 (4.5) |
| FSGS | 2 (4.5) |
| PDG | 1/44 (2.3) |
BKPyVAN, BK polyomavirus-associated nephropathy; Ptc, peri-tubular capillaritis; CNI, calcineurin inhibitor; FSGS, focal segmental glomerular sclerosis; PDG, pediatric donor glomerulopathy.