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. 2020 Aug;8(15):918. doi: 10.21037/atm-20-944

Table 3. Correlation coefficients between sputum autoantibody levels and clinical parameters in COPD patients (adjusted by age).

Sputum autoantibodies FEV1 (%predicted) CAT mMRC Number of exacerbations in the previous year
r P r P r P r P
Anti-Sm 0.101 0.504 0.182 0.226 0.026 0.864 0.115 0.448
Anti-P0 –0.045 0.766 0.421 0.004 0.190 0.205 0.370 0.011
Anti-Ro/SSA –0.005 0.973 0.338 0.022 0.191 0.203 0.382 0.009
Anti-La/SSB 0.021 0.888 –0.058 0.701 0.025 0.871 0.025 0.869
Anti-Scl70 –0.083 0.584 0.041 0.787 0.167 0.266 0.174 0.246
Anti-Jo1 –0.197 0.191 0.085 0.576 0.122 0.419 0.268 0.072
Anti-TPO 0.244 0.103 –0.118 0.435 –0.169 0.262 –0.182 0.227
Anti-MPO –0.111 0.463 0.309 0.037 0.159 0.292 0.206 0.171
Anti-PR3 –0.303 0.041 0.291 0.050 0.237 0.113 0.304 0.040
Anti-U1-SnRNP –0.006 0.969 0.352 0.016 0.157 0.298 0.367 0.012

COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; CAT, COPD assessment test; mMRC, modified Medical Research Council Dyspnea Scale; Sm, Smith antigen; P0, ribosomal phosphoprotein P0; Ro/SSA, Ro/Sjögren syndrome type A antigen; La/SSB, La/Sjögren syndrome type B antigen; Scl-70, DNA topoisomerase I; Jo-1, histidyl-tRNA synthetase; U1-SnRNP, U1 small nuclear ribonucleoprotein; TPO, thyroid peroxidase; PR-3, proteinase-3; MPO, myeloperoxidase.