Table 2. Demographic and clinical characteristics of patients with stable IPF and patients with AE-IPF.
| Characteristics | Stable IPF (n=49) | AE-IPF (n=34) | P value |
|---|---|---|---|
| Men/women | 39/10 | 26/8 | 0.734 |
| Age, years (mean ± SD) | 66.39±1.26 | 67.65±1.29 | 0.471 |
| Smoking status | |||
| Never-smoker | 13 | 7 | 0.534 |
| Former smoker | 32 | 26 | 0.276 |
| Current smoker | 4 | 1 | 0.325 |
| 6MWD | 297.73±104.59 | ND | – |
| FEV1 (% predicted) | 68.70±20.62 | ND | – |
| FVC (% predicted) | 65.54±20.08 | ND | – |
| DLCO (% predicted) | 44.93±19.10 | ND | – |
| CT visual score | |||
| GGO Score (%) | 6.020±0.46 | 17.44±1.42 | <0.0001 |
| Fibrosis Score (%) | 18.86±1.182 | 25.41±1.95 | 0.003 |
| Serum KL-6 (U/mL) | 1,496±59.57 | 1,958±61.51 | <0.0001 |
ND, no detected; AE-IPF, acute exacerbation of idiopathic pulmonary fibrosis; 6MWD, 6-minute walk distance; FEV1, forced expiratory volume in 1; FVC, forced vital capacity; DLCO, carbon monoxide diffusing capacity; GGO, ground glass opacification.