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. 2020 Aug;8(16):995. doi: 10.21037/atm-20-5192

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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MiR-182-5p targets and negatively regulates FBXW7. (A) The expression of FBXW7 in TNBC tissues was examined by qRT-PCR. (B) Pearson correlation analysis was performed to identify the correlation between miR-182-5p and FBXW in TNBC tissues. (C) The schematic diagram reflected the complementary binding sites between miR-182-5p and FBXW. (D) Dual-luciferase reporter gene assay showed the luciferase activity in TNBC cells. (E) The expression of FBXW7 in TNBC cells was measured by Western blot assay. **, P<0.01; ***, P<0.001. TNBC, triple-negative breast cancer.