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Tet mitigates renal inflammation in STZ-induced DN rats. The productions of IL-6 (A), iNOS (B), TNF-α (C) and IL-10 (D) in kidneys tissue were detected by ELISA kits. (E) The generation of ROS (×200). (**, P<0.01 versus the control group; #, P<0.05, ##, P<0.01 versus the DN model group). STZ, streptozotocin; DN, diabetic nephropathy; Tet, tetrandrine; IL-6, interleukin-6; iNOS, inducible nitric oxide synthase; TNF-α, tumor necrosis factor-α; IL-10, interleukin-10.
