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Representative images before and after apatinib treatment in case 1. In this 48-year-old man with primary hepatocellular carcinoma, baseline contrast-enhanced CT (A) demonstrates multifocal tumors. After 8 weeks of therapy with apatinib. Multifocal tumors have decreased in density and size (B), showing greater homogeneity and better defined margins. Findings at follow-up CT represent response according to CT-morphologic criteria.
