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. 2020 Aug;8(16):997. doi: 10.21037/atm-20-5171

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Hub genes positively correlated with GFR in DKD patients. (A) The expression of EGF positively correlated with GFR (P<0.001, r=0.666). (B) The expression of KNG1 positively correlated with GFR (P<0.001, r=0.780). (C) The expression of GADD45B positively correlated with GFR (P<0.001, r=0.753). (D) The expression of CDH2 positively correlated with GFR (P=0.016, r=0.730). CG, Cockcroft Gault; DKD, diabetic kidney disease; GFR, glomerular filtration rate; MDRD, modification of diet in renal disease; mRNA, messenger RNA.