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CPEs of HCoV-229E in cultured Huh7 cells and SARS-CoV-2 in cultured Vero E6 cells, 100×. (A) CPEs of HCoV-229E in cultured Huh7 cells after 72 h. The cells became rounded and aggregated, and some cells began to detach or fuse. (B) CPEs of SARS-CoV-2 in cultured Vero E6 cells after 48 h. There were few cytopathic changes, and the cells became rounded or irregular in shape and aggregated. CPEs, cytopathic effects.
