Figure 1.

circ_0003738 Was Upregulated in Psoriatic Tregs

(A) Boxplots were applied to visualize the distributions of circRNAs from the six samples. (B) Heatmap showed differentially expressed circRNAs between the two groups. Red spot stands for upregulation, and green spot stands for downregulation. (C) Scatterplot showed the variations of circRNA expressions in psoriatic Tregs (y axis) and normal Tregs (x axis). The values are the averaged normalized signal values of each group (log2 scaled). (D) Volcano plot of differentially expressed circRNAs. (E) Quantitative real-time PCR analysis of circRNAs expression in Tregs from psoriatic patients (n = 8) and normal controls (n = 6). Data are representative of means ± SEMs. ∗p < 0.05.