Table 1. Ninety-six significantly down-regulated and 133 significantly up-regulated miRNAs in SCI-1 group compared to NC group.
| miRNA | log2-ratio (SCI-1/NC) | P value |
|---|---|---|
| miR-139-5p | −3.102182882 | 1.75E-56 |
| miR-21-5p | 2.221163332 | 1.35E-49 |
| miR-466c-5p | 3.184432599 | 2.95E-42 |
| miR-125a-5p | −1.829219179 | 1.80E-41 |
| miR-149-5p | −2.143417515 | 2.49E-37 |
| miR-1-3p | −2.194065038 | 1.02E-34 |
| miR-181a-5p | −1.623090527 | 3.15E-33 |
| miR-145-5p | −2.367867781 | 4.84E-33 |
| miR-411-5p | 2.866397294 | 4.01E-32 |
| miR-132-3p | 2.337233687 | 1.42E-30 |
| miR-298-5p | 3.050317374 | 1.67E-30 |
| miR-328a-3p | −1.91132018 | 7.08E-30 |
| miR-129-5p | −2.684218688 | 1.19E-29 |
| miR-133a-3p | −2.639745931 | 3.86E-29 |
| miR-382-3p | 3.083780543 | 1.81E-28 |
| miR-495 | 3.246664284 | 1.49E-27 |
| miR-132-5p | 2.637582812 | 3.47E-26 |
| miR-379-5p | 2.713173134 | 3.87E-26 |
| miR-212-3p | 3.166034219 | 1.23E-25 |
| miR-379-3p | 2.891056501 | 1.52E-25 |
| miR-411-3p | 3.093952173 | 2.15E-25 |
| miR-139-3p | −2.428682251 | 4.64E-25 |
| miR-29c-5p | −2.259756176 | 4.76E-25 |
| miR-1193-3p | 3.095183493 | 7.12E-25 |
| miR-376b-3p | 3.811300461 | 3.84E-23 |
| miR-212-5p | 2.698225438 | 1.46E-22 |
| miR-15b-3p | 2.48316802 | 3.42E-22 |
| miR-320-3p | −1.678142165 | 3.77E-22 |
| miR-494-3p | 2.782278241 | 4.84E-22 |
| miR-540-3p | 2.538638666 | 1.25E-21 |
| miR-493-5p | 2.588627944 | 3.42E-21 |
| miR-434-5p | 2.665719473 | 5.01E-21 |
| miR-134-5p | 2.399485438 | 5.71E-21 |
| miR-431 | 2.280672634 | 1.87E-20 |
| miR-341 | 2.091476704 | 3.20E-20 |
| miR-99b-5p | −1.332158911 | 6.20E-20 |
| miR-133b-3p | −2.39189828 | 5.72E-19 |
| miR-204-5p | −1.959297741 | 5.85E-19 |
| miR-129-1-3p | −2.892021806 | 8.06E-19 |
| let-7d-3p | −1.636823106 | 9.13E-19 |
| miR-29b-5p | −2.447544506 | 9.97E-19 |
| miR-410-3p | 2.213844944 | 1.11E-18 |
| miR-299a-3p | 2.584887153 | 1.24E-18 |
| miR-338-5p | −2.041548097 | 1.87E-18 |
| miR-466b-5p | 2.878992417 | 2.83E-18 |
| miR-1b | −1.75345764 | 9.93E-18 |
| miR-299b-3p | 2.572487155 | 1.16E-17 |
| miR-296-3p | 3.946209334 | 1.40E-17 |
| miR-127-5p | 2.144357263 | 3.13E-17 |
| miR-181d-5p | −1.481396568 | 3.28E-17 |
| miR-370-3p | 1.940524375 | 4.39E-17 |
| miR-30c-2-3p | −1.46199406 | 5.88E-17 |
| miR-409a-3p | 2.003956093 | 4.11E-16 |
| miR-130b-5p | 1.90853073 | 4.59E-16 |
| miR-184 | 2.346878698 | 4.61E-16 |
| miR-543-3p | 1.906948855 | 7.94E-16 |
| miR-300-3p | 2.067638501 | 8.03E-16 |
| miR-29a-3p | −1.037912307 | 9.18E-16 |
| miR-409a-5p | 2.179408619 | 1.30E-15 |
| miR-1249 | −1.889683111 | 1.63E-15 |
| miR-23b-3p | −1.555750442 | 2.12E-15 |
| miR-380-3p | 3.30194013 | 3.54E-15 |
| miR-143-5p | −1.477749401 | 3.95E-15 |
| miR-127-3p | 1.460866685 | 6.67E-15 |
| miR-150-5p | −1.682559818 | 4.99E-14 |
| miR-541-5p | 2.132434591 | 5.02E-14 |
| miR-221-3p | 1.369736139 | 5.67E-14 |
| miR-337-5p | 1.679642486 | 5.92E-14 |
| miR-452-5p | 2.848340092 | 9.00E-14 |
| miR-125b-5p | −1.083888826 | 1.05E-13 |
| let-7e-3p | −1.450696119 | 1.16E-13 |
| miR-30a-3p | −1.155344661 | 1.59E-13 |
| miR-504 | −2.292273523 | 1.77E-13 |
| miR-223-5p | 2.302263875 | 1.88E-13 |
| miR-378b | −1.209495332 | 2.91E-13 |
| miR-503-5p | 1.430411192 | 3.19E-13 |
| miR-708-5p | −1.719135844 | 3.87E-13 |
| miR-211-5p | −1.863725451 | 4.51E-13 |
| miR-31a-5p | 1.460585107 | 4.80E-13 |
| miR-378a-5p | −1.269112031 | 5.68E-13 |
| let-7e-5p | −1.133920645 | 7.24E-13 |
| miR-496-3p | 2.541231703 | 7.40E-13 |
| miR-378a-3p | −1.212208456 | 9.26E-13 |
| miR-140-5p | 1.346569902 | 1.70E-12 |
| miR-330-3p | −1.575317256 | 2.24E-12 |
| miR-155-5p | 1.491246802 | 4.30E-12 |
| miR-223-3p | 1.787455625 | 4.88E-12 |
| miR-322-5p | 1.679814718 | 8.14E-12 |
| miR-770-3p | 1.980950727 | 2.36E-11 |
| miR-342-3p | −1.567011952 | 4.32E-11 |
| miR-676 | −1.569928685 | 4.43E-11 |
| miR-218a-5p | 1.331073023 | 4.76E-11 |
| miR-450a-5p | 1.295604623 | 1.03E-10 |
| miR-505-3p | −1.336336399 | 1.12E-10 |
| miR-9a-5p | −1.316114776 | 1.25E-10 |
| miR-423-5p | −1.037698356 | 1.45E-10 |
| miR-142-5p | 1.720418902 | 1.56E-10 |
| miR-146b-5p | 1.479442337 | 1.91E-10 |
| miR-450b-5p | 1.220783652 | 2.94E-10 |
| miR-542-3p | 1.667710786 | 4.17E-10 |
| miR-331-3p | −1.23153033 | 5.48E-10 |
| miR-493-3p | 1.888123357 | 7.97E-10 |
| miR-193a-5p | −1.306363196 | 8.38E-10 |
| miR-181b-5p | −1.029122766 | 8.74E-10 |
| miR-26b-3p | −1.620736939 | 9.29E-10 |
| miR-433-3p | 1.333581542 | 1.31E-09 |
| miR-31a-3p | 2.320944268 | 1.62E-09 |
| miR-758-3p | 2.375835876 | 2.13E-09 |
| miR-29c-3p | −1.334293219 | 2.86E-09 |
| miR-361-3p | −1.067846562 | 5.43E-09 |
| miR-511-3p | 1.768513538 | 5.83E-09 |
| miR-374-5p | 1.057767481 | 7.12E-09 |
| miR-363-3p | 1.167009367 | 9.19E-09 |
| miR-466b-4-3p | 3.573146084 | 1.41E-08 |
| miR-466b-2-3p | 3.573146084 | 1.41E-08 |
| miR-17-5p | 1.35661569 | 2.26E-08 |
| miR-434-3p | 1.112430116 | 2.51E-08 |
| miR-330-5p | −1.272071423 | 3.05E-08 |
| miR-126a-3p | 1.105891785 | 3.19E-08 |
| miR-193b-3p | −1.193427185 | 4.13E-08 |
| miR-485-3p | 1.309238138 | 4.16E-08 |
| miR-652-3p | −1.151824972 | 4.25E-08 |
| miR-664-2-5p | −1.325200111 | 4.49E-08 |
| miR-181c-5p | −1.344033479 | 5.11E-08 |
| miR-124-3p | −2.736550476 | 5.53E-08 |
| miR-296-5p | 1.94671836 | 5.92E-08 |
| miR-664-3p | −1.280718524 | 7.10E-08 |
| miR-369-5p | 1.704897781 | 8.05E-08 |
| let-7i-3p | −1.144553333 | 1.01E-07 |
| miR-30c-1-3p | −1.141885436 | 1.41E-07 |
| miR-376a-5p | 2.898910594 | 1.45E-07 |
| miR-136-3p | 2.276879909 | 2.03E-07 |
| miR-147 | 4.722615042 | 2.07E-07 |
| miR-324-5p | −1.474568556 | 2.09E-07 |
| miR-383-5p | −1.367148471 | 3.87E-07 |
| miR-369-3p | 2.419026089 | 4.14E-07 |
| miR-1306-5p | −1.143077487 | 4.41E-07 |
| miR-665 | 2.72800571 | 6.66E-07 |
| miR-365-3p | −1.154939824 | 7.90E-07 |
| miR-1843a-3p | −1.186555516 | 8.82E-07 |
| miR-466b-3p | 2.014219539 | 1.01E-06 |
| miR-210-3p | −1.243918488 | 1.04E-06 |
| miR-133a-5p | −1.421989127 | 1.15E-06 |
| miR-24-1-5p | −1.168682039 | 1.39E-06 |
| miR-382-5p | 1.129487387 | 1.93E-06 |
| let-7b-3p | −1.115343686 | 2.07E-06 |
| miR-326-3p | −1.333250513 | 2.08E-06 |
| miR-346 | −2.187914853 | 2.27E-06 |
| miR-582-3p | 1.155652793 | 2.62E-06 |
| miR-29b-3p | −1.175745009 | 3.11E-06 |
| miR-380-5p | 2.227842964 | 3.16E-06 |
| miR-146b-3p | 1.133080107 | 3.17E-06 |
| miR-129-2-3p | −2.216258422 | 3.54E-06 |
| miR-99a-3p | −1.898295287 | 5.38E-06 |
| miR-3577 | −1.450639165 | 6.42E-06 |
| miR-154-5p | 1.303208005 | 6.67E-06 |
| miR-206-3p | −1.425103365 | 7.05E-06 |
| miR-338-3p | −1.139524526 | 7.92E-06 |
| miR-299a-5p | 1.493976295 | 9.67E-06 |
| miR-7a-1-3p | 1.448137132 | 1.26E-05 |
| miR-3559-5p | 1.157007276 | 1.27E-05 |
| miR-217-5p | −1.060663628 | 1.86E-05 |
| miR-34c-5p | 1.165838023 | 1.93E-05 |
| miR-34b-5p | 1.35654223 | 3.37E-05 |
| miR-708-3p | −1.298912776 | 3.62E-05 |
| miR-329-3p | 1.011931442 | 4.03E-05 |
| miR-324-3p | −1.056232828 | 4.14E-05 |
| miR-1247-3p | 1.439598936 | 4.23E-05 |
| miR-204-3p | −1.603099354 | 5.53E-05 |
| miR-3594-3p | −2.097600786 | 5.83E-05 |
| miR-3102 | −1.301393539 | 6.19E-05 |
| miR-675-3p | 5.376720886 | 6.25E-05 |
| miR-298-3p | 1.666250663 | 9.25E-05 |
| miR-3064-5p | −1.386971792 | 0.0001146 |
| miR-135b-5p | −1.018638112 | 0.00011753 |
| miR-6329 | 1.253243538 | 0.00012762 |
| miR-130b-3p | 1.906869385 | 0.00014886 |
| miR-3099 | −2.879178527 | 0.00016084 |
| miR-138-1-3p | −1.694585122 | 0.00017551 |
| miR-362-5p | 1.107395298 | 0.00018552 |
| miR-376b-5p | 1.388725246 | 0.00019653 |
| miR-20b-5p | 2.411053913 | 0.00035965 |
| miR-673-3p | 1.645167515 | 0.00041933 |
| miR-203b-3p | 2.187699694 | 0.0004772 |
| miR-146a-3p | 3.056395912 | 0.00052588 |
| miR-20a-5p | 1.074404903 | 0.00054571 |
| miR-21-3p | 1.28424385 | 0.00086862 |
| miR-667-5p | 2.138578479 | 0.00087156 |
| miR-582-5p | 1.726650312 | 0.00087391 |
| miR-377-3p | 4.707555166 | 0.00097947 |