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. 2020 Aug 6;13(16):3466. doi: 10.3390/ma13163466

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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PPP and buffy coat but not heated PPP caused the accumulation of IL11 in the oral fibroblast cells supernatant. Gingival fibroblasts were exposed to 30% of the respectively lysates prepared from PPP, heated PPP (75 °C for 10 min; Alb-gel), and buffy coat (BC). For red clot, 5% of the lysates was used. The levels of IL11 in the supernatant of the fibroblasts is presented in ng/mL. Bar graphs show the means and standard deviation of three independent experiments (N = 3). Statistical analysis was based on an ANOVA with a multiple comparison against heated PPP based on Fischer’s LSD test.