Table 2.

Differentially expressed miRNAs by miRNA profiling in the serum of patients with NSCLC vs. control groups

miRNAs	NSCLC vs. all controls			NSCLC vs. OLs			NSCLC vs. HPs
	Differential expression	Fold change	P-value	Differential expression	Fold change	P-value	Differential expression	Fold change	P-value
MiR-769	−12.630	6.34 × 103	0.005	−16.653	1.03 × 105	0.007	−8.606	3.90 × 102	0.062
MiR-339-3p	−10.242	1.21 × 103	0.009	−10.597	1.55 × 103	0.017	−9.887	9.47 × 102	0.062
MiR-339-5p	−7.935	2.45 × 102	0.021	−6.588	9.62 × 101	0.089	−9.283	6.23 × 102	0.042
MiR-519a	−5.338	4.05 × 101	0.093	−3.303	9.87 × 10	0.734	−7.374	1.66 × 102	0.017
MiR-1238	6.210	1.35 × 10−2	0.036	4.130	5.71 × 10−2	0.234	8.289	3.20 × 10−3	0.027
MiR-99a#	6.341	1.23 × 10−2	0.036	4.087	5.89 × 10−2	0.234	8.596	2.58 × 10−3	0.027
MiR-134	6.711	9.54 × 10−3	0.059	10.302	7.92 × 10−4	0.027	3.121	1.15 × 10−1	0.396
MiR-604	6.722	9.47 × 10−3	0.059	12.594	1.62 × 10−4	0.011	0.851	5.55 × 10−1	0.610
MiR-539	7.976	3.97 × 10−3	0.059	11.786	2.83 × 10−4	0.042	4.166	5.57 × 10−2	0.308
MiR-342	10.047	9.46 × 10−4	0.027	9.930	1.02 × 10−3	0.089	10.163	8.72 × 10−4	0.062

HPs, healthy persons; NSCLC, non-small cell lung cancer; OLs, other lung diseases.