Figure 4.
B cell markers (CD19, CD22 and PAX5), CD4+ T cell markers (CD4), CD8+ T cell maker (CD8), Macrophage markers (ITGAM/CD11b, CD68 and CD163), Neutrophil markers (FUT4/CD15) and Dendritic cell markers (CD1a, CD83 and ITGAE/CD103) were selected in the GEPIA TCGA glioma database. IL13RA2 mRNA expression level is positively correlated with macrophage [(A) ITGAM/CD11b (R=0.21, P<0.001), (B) CD68 (R=0.19, P<0.001), (C) CD163 (R=0.21, P<0.001)]; CD4+ T cell [(D) CD4 (R=0.21, P<0.001)]; CD8+ T cell [(E) CD8A (R=0.24, P<0.001)]; neutrophil [(F) FUT4/CD15 (R=0.26, P<0.001)] and dendritic cell [(G) CD1A (R=0.079, P=0.04), (H) CD83 (R=0.15, P<0.001), (I) ITGAE/CD103 (R=0.31, P<0.001)] infiltration, but no correlation was found between B cell markers [(J) CD19 (P=0.16), (K) CD79A (P=0.43), (L) PAX5 (P=0.39)] and IL13RA2 in the GEPIA TCGA glioma data sets. TPM = Transcripts Per Kilobase Million.