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. 2020 Aug 15;12(8):4728–4738.

Figure 2.

Figure 2

Knockdown of circ_0007142 suppressed proliferation, migration and invasion, induced apoptosis in lung adenocarcinoma cells. A. Circ_0007142 expression level was remarkably enhanced in cancer cell lines than that in normal cell line. B. Circ_0007142 knockdown was established via siRNA transfection in A549 and H125 cell. C. CCK-8 assay revealed circ_0007142 knockdown inhibited the proliferation of A549 and H125 cells significantly. D. Flow cytometry revealed that silencing of circ_0007142 markedly augmented apoptosis in cells compared with the non-transfected cells. E. Colony formation assay showed circ_0007142 silencing decreased the colony forming ability of two cell lines. F. Transwell assay showed circ_0007142 silencing inhibited the migration and invasion ability of cells. *P<0.05 compared to BEAS-2B, si-NC group; **P<0.01 compared to BEAS-2B.